“TRP inflammation” relationship in cardiovascular system

Role of TRP channels in the cardiovascular system

Yue Z, Xie J, Yu AS, Stock J, Du J, Yue L. Role of TRP channels in the cardiovascular system. Am J Physiol Heart Circ Physiol 308: H157–H182, 2015. First published November 19, 2014; doi:10.1152/ajpheart.00457.2014.—The transient receptor potential (TRP) superfamily consists of a large number of nonselective cation channels with variable degree of Ca -permeability. The 28 mammalian TRP channel ...

Emerging concepts for the role of TRP channels in the cardiovascular system.

The transient receptor potential (TRP) family of ion channels is a large family of cation selective ion channels, which are expressed and functional in a variety of tissues. In this review we focus on the most recent results detailing the role of TRP channels in the cardiovascular system. The presented results underscore the role of TRP channels in cardiomyocytes, smooth cells and endothelium, ...

TRP Channel Cannabinoid Receptors in Skin Sensation, Homeostasis, and Inflammation

In the skin, cannabinoid lipids, whether of endogenous or exogenous origin, are capable of regulating numerous sensory, homeostatic, and inflammatory events. Although many of these effects are mediated by metabotropic cannabinoid receptors, a growing body of evidence has revealed that multiple members of the transient receptor potential (TRP) ion channel family can act as "ionotropic cannabinoi...

Inflammation in Cardiovascular Disease

In 1998, I wrote an editorial that attempted to make two points.2 The first point was biological: there existed at that time an active debate over whether inflammation was a cause or a result of cardiovascular disease (CVD), and I suggested that this debate was in fact based on a false distinction, and that both positions where likely to be correct. While atherothrombotic disease is inflammator...

Inflammation in Cardiovascular Disease